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Major sources of increase in air pollutant concentration in the ambient air are due to rapid industrialization and urbanization along with the growth in emission from automobiles. In the present study ambient air quality has been monitored for Oxides of Nitrogen (NOx), Sulphur dioxide (SO2), Particulate Matters - PM10 and PM2.5 by considering a typical rubber reclamation Plant, Mysuru as a source of emission. ISCST3 an air pollutant dispersion model has been used to predict the dispersion of air pollutant concentrations such as, NOx, SO2, and PM10. The monitoring of ambient air was revealed that, at JSS Urban Haat, the PM10 and PM2.5 concentrations were found to be 60 µg/m3 and 30 µg/m3, respectively. The maximum PM10 and PM2.5 concentration was observed at JSS urban Haat (R4). The lowest concentration of PM10 and PM2.5 of 50 µg/m3 and 19 µg/m3 was noticed at Health Care Centre (R2) and Dexter Logistics (R3), respectively. Results of ISCST3 dispersion model run showed maximum PM10 of 0.12634 µg/m3 was observed at JSS Urban Haat and maximum SO2 concentration was found to be of 0.0618 µg/m3 at Health Care Centre. Further, predicted concentrations were found to be less than the observed concentrations, which may be due to the fact that, the model prediction considered the emissions from two stacks of rubber reclamation industrial Plant, and not being considered from other industrial emissions as well as automobiles.